Mix ingredients: In a small saucepan, combine ketchup, brown sugar, apple cider vinegar, Worcestershire sauce, garlic powder, onion powder, black pepper, and smoked paprika (if using).
Heat gently: Place over medium heat and stir occasionally until the sugar dissolves and sauce comes to a gentle simmer.
Simmer: Cook for 5–7 minutes, stirring occasionally, until slightly thickened. Taste and adjust seasoning if needed.
Cool slightly: Remove from heat and let it rest for a few minutes to thicken further.
Serve or store: Pour generously over meatloaf or store in an airtight container in the fridge for up to 1 week.
